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12_F-Y Cheng

姓    名   鄭豐裕 助理教授
聯絡電話(辦公室)   (02)-28610511#25312
教    研   室   大義館1F    107-1
學    歷   國立成功大學化學博士
研究領域與專長   分析化學、奈米材料合成與應用、奈米生物醫學

Selected publications (SCI):

  1. Chia-Hao Su, Ching-Yi Tsai, Boguslaw Tomanek, Wei-Yu Chen, Fong-Yu Cheng*, “Evaluation of Blood-Brain Barrier-Stealth Nanocomposites for in situ Glioblastoma Theranostic Applications”, Nanoscale 2016, 8, 7866-7870. (IF = 7.76; CHEMISTRY, MULTIDISCIPLINARY - Ranking:18/163; NANOSCIENCE & NANOTECHNOLOGY - Ranking:12/83)
  2. Chia-Hao Su, Fong-Yu Cheng*, “In vitro and in vivo applications of alginate/iron oxide nanocomposites for theranostic molecular imaging in brain tumor model”, RSC Advances, 2015, 5, 90061-90064. (IF = 3.289; CHEMISTRY, MULTIDISCIPLINARY - Ranking:48/163)
  3. Ping-Ching Wu, Dar-Bin Shieh, Fong-Yu Cheng*, “Nanomaterial-mediated photothermal cancer treatment: the pivotal role of cellular uptake of nanomaterials on photothermal therapeutic efficacy”, RSC Advances, 2014, 4 (95), 53297 – 53306. (IF = 3.289; CHEMISTRY, MULTIDISCIPLINARY - Ranking:48/163)
  4. Keng-Shiang Huang, Dar-Bin Shieh, Chen-Sheng, Yeh, Ping-Ching Wu*, Fong-Yu Cheng*, “Antimicrobial applications of water-dispersible magnetic nanoparticles in biomedicine (review article)”, Current Medicinal Chemistry, 2014, 21, 3312-3322. (IF = 3.455; CHEMISTRY, MEDICINAL - Ranking:10/59)
  5. Ming-Hua Hsu*, Hong Chuang, Fong-Yu Cheng, Ying-Pei Huang, Chien-Chung Han, Su-Chin Huang, Jen-Kun Chen, Dian-Syue Wu, Hsueh-Liang Chu, and Chia-Ching Chang, “Directly thiolated modification onto the surface of detonation nanodiamonds”, ACS Applied Materials & Interfaces, 2014, 6, 7198-7203. (IF = 7.145; MATERIALS SCIENCE, MULTIDISCIPLINARY - Ranking:25/271; NANOSCIENCE & NANOTECHNOLOGY - Ranking:14/83)
  6. Ming-Hua Hsu*, Hong Chuang, Fong-Yu Cheng, Ying-Pei Huang, Chien-Chung Han, Kuan-Chuan Pao, Shih-Ching Chou, Fa-Kuen Shieh, Fu-Yuan Tsai, Chung-Chang Lin, Dian-Syue Wug and Chia-Ching Chang, “Simple and highly efficient direct thiolation of the surface of carbon nanotubes”, RSC Advances, 2014, 4, 14777-14780. (IF = 3.289; CHEMISTRY, MULTIDISCIPLINARY - Ranking:48/163)
  7. Yu-Hsuan Lee, Fong-Yu Cheng, Hui-Wen Chiu1, Jui-Chen Tsai, Chun-Yong Fang, Chun-Wan Chen* and Ying-Jan Wang*, “Cytotoxicity, oxidative stress, apoptosis and the autophagic effects of silver nanoparticles in mouse embryonic fibroblasts”, Biomaterials, 2014, 35, 4706-4715. (IF =8.387; MATERIALS SCIENCE, BIOMATERIALS - Ranking:1/33)
  8. Tsai,M. F., Chang, S. H., Cheng, F. Y., Shanmugam , V., Cheng, Y. S., Su,C. H., Yeh, C. S.*, ” Au Nanorod Design as Light-Absorber in the First and Second Biological Near-Infrared Windows for In Vivo Photothermal Therapy ” , ACS Nano, 2013, 7 (6), 5330–5342. (IF = 13.334; CHEMISTRY, MULTIDISCIPLINARY - Ranking:8/163; NANOSCIENCE & NANOTECHNOLOGY - Ranking:4/83)
  9. Chang, M. Y., Yang, Y. J., Chang, C. H., Tang, A. C., Liao, W. Y., Cheng, F. Y., Yeh, C. S., Lai, J. J., Stayton, P. S., Hsieh, P. C.. “Functionalized nanoparticles provide early cardioprotection after acute myocardial infarction”,  Journal of Controlled Release. 2013, 170(2), 287-294. (IF = 7.441; CHEMISTRY, MULTIDISCIPLINARY - Ranking:19/163)
  10. Fan, N. C., Cheng, F. Y., Ho, J. A.*, Yeh, C. S.*, “Photocontrolled Targeted Drug Delivery: Photocaged Biologically Active Folic Acid as a Light-Responsive Tumor-Targeting Molecule”, Angew. Chem. Int. Ed., 2012, 51, 8806-8810. (equal contribution to first author) (IF = 11.709; CHEMISTRY, MULTIDISCIPLINARY - Ranking:11/163)
  11. Yi-Ting Chang, Pei-Yi Liao, Hwo-Shuenn She,Yu-Jui Tseng, Fong-Yu Cheng*,and Chen-Sheng Yeh*, “Near-infrared light-responsive intracellular drug and siRNA release using Au nanoensembles with oligonucleotide-capped silica shell”, Advanced Materials 2012, 24(25), 3309-3314. (selected as very important and very urgent paper) (selected as journal cover picture) (IF = 18.96; CHEMISTRY, MULTIDISCIPLINARY - Ranking:6/163; NANOSCIENCE & NANOTECHNOLOGY - Ranking:2/83)
  12. Su, W. P., Cheng, F. Y., Shieh, D. B., Yeh, C. S., Su, W. C., “PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells”,  International Journal of Nanomedicine, 2012, 7, 4269-4283. (IF = 4.32; NANOSCIENCE & NANOTECHNOLOGY - Ranking:26/83)
  13. Cheng, F. Y., Hu, K. W., Yeh, C.S.*, " Formation of Ag nanoframes with facilitation of dithiols ", Journal of Nanoscience and Nanotechnology , 2012, 12, 2548-2556. (IF = 1.338; NANOSCIENCE & NANOTECHNOLOGY - Ranking:61/83)
  14. Huang, C. C., Tsai, C.Y., Sheu, H. S., Chuang, K.Y., Cheng, F.Y., Su, C.H., Lei, H.Y., and Yeh, C.S.*, " Enhancing Transversal Relaxation for Magnetite Nanoparticles in MR Imaging Using Gd3+-chelated Mesoporous Silica Shells ", ACS Nano , 2011, 5, 3905-3916. (IF = 13.334; CHEMISTRY, MULTIDISCIPLINARY - Ranking:8/163; NANOSCIENCE & NANOTECHNOLOGY - Ranking:4/83)
  15. Cheong, S., Ferguson, P., Feindel, K.W., Hermans, I.F., Callaghan, P.T., Meyer, C., Slocombe, A., Su, C.H., Cheng, F.Y., Yeh, C. S., Ingham, B., Toney, M.F., Tilley, R.D.*, "Simple Synthesis and Functionalization of Iron Nanoparticles for Magnetic Resonance Imaging", Angew. Chem. Int. Ed., 2011, 50, 4206-4209. (IF = 11.709; CHEMISTRY, MULTIDISCIPLINARY - Ranking:11/163)
  16. Cheng, F.Y., Su, C.H., Wu, P.C., Yeh, C.S.*, " Multifunctional polymeric nanoparticles for combined chemotherapeutic and near-infrared photothermal cancer therapy in vitro and in vivo", Chem. Commun., 2010, 46, 3167-3169 (selected in Highlight in Chemical Biology) (IF = 6.567; CHEMISTRY, MULTIDISCIPLINARY - Ranking:21/163)
  17. Yang, S.Y., Cheng, F.Y., Yeh, C.S., Lee, G.B.*, "Size-controlled synthesis of gold nanoparticles using a micro-mixing system", Microfluidics and Nanofluidics 2010, 8, 303-311. (IF = 2.537; NANOSCIENCE & NANOTECHNOLOGY - Ranking:39/83)
  18. Cheng, F.Y., Chen, C.T., Yeh, C.S.*, "Comparative efficiencies of photothermal destruction of malignant cells using antibody-coated silica @ Au nanoshells, hollow Au/Ag nanospheres and Au nanorods", Nanotechnology 2009, 20, 425104. (IF = 3.573; NANOSCIENCE & NANOTECHNOLOGY - Ranking:30/83)
  19. Kuo, W.S., Hwang, S.M., Sei, H.T., Ku, Y.C., Hsu, L.F., Cheng, F.Y., Hsieh, C.H.,Yeh, C.S.*, " Stabilizer-Free Poly (lact ide-co-glycolide) Nanoparticles for Human Mesenchymal Stem Cell s Molecular Imaging", Journal of the Chinese Chemical Society 2009, 56(5), 940-948. (IF = 0.879; CHEMISTRY, MULTIDISCIPLINARY - Ranking:124/163)
  20. Kuo, W.S., Ku, Y.C., Sei, H.T., Cheng, F.Y., Su, W.C., Yeh, C.S.*, "Paclitaxel-Loaded Stabilizer-Free poly(D,L-lactide-co-glycolide) Nanoparticles Conjugated with Quantum Dots for Reversion of Anti-Cancer Drug Resistan ce and Cancer Cellular Imaging", J. Chin. Chem. Soc. 2009, 56(5), 923-934. (IF = 0.879; CHEMISTRY, MULTIDISCIPLINARY - Ranking:124/163)
  21. Lee, W.B., Weng, C.H., Cheng, F.Y., Yeh, C.S., Lei, H.Y., Lee, G.B.*, "Biomedical microdevices synthesis of iron oxide nanoparticles using a microfluidic system", Biomedical Microdevices, 2009, 11, 161-171. (IF = 2.227; NANOSCIENCE & NANOTECHNOLOGY - Ranking:41/83)
  22. Hwu, J.R.*, Lin, Y.S., Thainashmuthu Josephrajan, Hsu, M.H., Cheng, F.Y., Yeh, C.S., Su, W.C., and Shieh, D.B., "Targeted Paclitaxel by Conjugation to Iron Oxide and Gold Nanoparticles", J. Am. Chem. Soc. 2009, 131(1), 66-68. (IF = 13.038; CHEMISTRY, MULTIDISCIPLINARY - Ranking:10/163)
  23. Cheng, F. Y.; Saprina Wang, P. H.; Su, C. H.; Tsai, T. L.; Wu, P. C.; Shieh, D. B.; Chen, J. H.; Patrick Hsieh, C. H.; Yeh, C. S.*, "Stabilizer-free poly(lactide-co-glycolide) nanoparticles for multimodal biomedical probes", Biomaterials 2008, 29, 2104-2112. (IF =8.387; MATERIALS SCIENCE, BIOMATERIALS - Ranking:1/33)
  24. Ping-Ching Wu, Chia-Hao Su, Fong-Yu Cheng, Weng JC, Tsai TL, Chen-Sheng Yeh, Chen JH, Hwu JR, Tzeng Y, Wu-Chou Su, Dar-Bin Shieh*, Modularly Assembled Magnetite Nanoparticles Enhance in vivo Targeting for Magnetic Resonance Cancer Imaging. Bioconjugate Chemistry, 2008, 19 (10), 1972-1979. (IF = 4.5; CHEMISTRY, MULTIDISCIPLINARY - Ranking:30/163)
  25. Jeng, J. Y.; Lin, M. F.; Cheng, F. Y.; Yeh, C. S.; Shiea, J. T.*, "Using high-concentration trypsin-immobilized magnetic nanoparticles for rapid in situ protein digestion at elevated temperature", Rapid Communications in Mass Spectrometry. 2007, 21, 3060–3068. (IF = 2.226; CHEMISTRY, ANALYTICAL - Ranking:33/75)
  26. Shieh, D. B.; Su, C. H.; Cheng, F. Y.; Wu, Y. N.; Su, W. C.; Hwu, J. R.; Chen, J. H.; Yeh, C. S.*, "Aqueous Nickel- Nitrilotriacetate Modified Fe3O4-NH3+ Nanoparticles for Protein Purification and Cell Targeting", Nanotechnology, 2006, 17, 4174-4182. (IF = 3.573; NANOSCIENCE & NANOTECHNOLOGY - Ranking:30/83)
  27. Shieh, D. B.; Cheng, F. Y.; Su, C. H.; Yeh, C. S.*; Wu, M. T.; Tsai, C. Y.; Wu, C. L.; Chen, D. H.; Chou, C. H., "Aqueous dispersions of magnetite nanoparticles with NH3+ surfaces for magnetic manipulations of biomolecules and MRI contrast agents", Biomaterials, 2005 , 26 , 7183-7191. (equal contribution to first author) (IF =8.387; MATERIALS SCIENCE, BIOMATERIALS - Ranking:1/33)
  28. Cheng, F. Y.; Yang, Y. S.; Huang, W. H.; Yeh, C. S.*; Tsai, C. Y.; Wu, C. L.; Shieh, D. B., "Characterization of aqueous dispersions of Fe3O4 nanoparticles and their biomedical applications", Biomaterials, 2005, 26, 729-738. (IF =8.387; MATERIALS SCIENCE, BIOMATERIALS - Ranking:1/33)

Conferences and invited talks:

  1. Fong-Yu Cheng* “Blood-Brain Barrier-Permeating Nanocomposites for Brain Tumor Theranostics” The second cross-strait Workshop on Nano-biophotonics (第二屆海峽兩岸奈米生醫光電研討會), Xi’an, China, May, 2016. (Invited speaker and Chairman)
  2. Fong-Yu Cheng*, The 2016 EMN Bioinspired Materials Meeting (International conference), Kaohsiung, Taiwan, 2016, March 14-18. (Invited speaker)
  3. Wei-Peng Li, Chia-Hao Su, Fong-Yu Cheng* “Blood-Brain Barrier-Permeating Nanocomposites for Brain Tumor Theranostics” 2015 Annual Meeting of Chemical Society located in Taipai, Hualien.(中國化學年會,花蓮,東華大學), December, 2015.
  4. Chia-Hao Su and Fong-Yu Cheng, "Blood-Brain Barrier-Permeated Nanocomposites for Theranostic Molecular Imaging in Brain Tumor" 2015 World Molecular Imaging Congress, Hawaii, USA, 2015, Sep. (Exhibitor Selected Posters Award)
  5. Fong-Yu Cheng*,The 2nd International Institute of Macromolecular Analysis and Nanomedicine Innovation Symposium and Hands-on Workshop, March, 2014(第二屆國際巨分子結構分析研討會暨工作坊) (Invited speaker)
  6. Fong-Yu Cheng*, Dar-Bin Shieh and Ping-Ching Wu, “The impact of endocytosis on photothermal therapeutic efficacy in nanomaterial-mediated photothermal cancer treatment.” Materials Today Asia, International Conference, 2014.
  7. Ping-Ching Wu, Dar-Bin Shieh and Fong-Yu Cheng* “Development of High Sensitive Color-Generating Reagent for Colloid-Au Based Lateral Flow Test Strip (LFTS) System” The 9th Taiwan/U.S. Air Force Nanoscience Workshop April, 2012.
  8. Fong-Yu Cheng, Dar-Bin Shieh and Ping-Ching Wu *. “Development of Nano High-Contrast Agent with Specific Targeting for MRI systems” The 9th Taiwan/U.S. Air Force Nanoscience Workshop April, 2012.
  9. Lien-Yu Hung, Fong-Yu Cheng, Chih-Chia Huang, Yi-Che Tsai, Chen-Sheng Yeh, Huan-Yao Lei and Gwo-Bin Lee*, “ Microfluidic System for Rapid Detection of Influenza Infection by Utilizing Magnetic MnFe2O4 Nanoparticle-based Immunoassay”, IEEE MEMS 2012 Conference - March 5 - 8, 2012.

NSC/MOST grands:

  1. 科技部多年期研究計畫『製備具產生氧氣功能之過氧化鈣奈米粒子及其生物醫學應用』,2015/08/01 ~ 2017/7/31 (主持人,MOST 104-2113-M-006 -015-MY2).
  2. 科技部多年期國際合作研究計畫『應用於腦癌之高效能與專一性標靶磁振造影顯影劑與區域性疾病控制製劑之研發』,2015/01/01 ~ 2017/12/31 (主持人,MOST 104-2923-M-006-002-MY3).
  3. 科技部多年期研究計畫『以高特異性組織標靶奈米粒子包覆抗小分子核糖核苷酸為治療策略以探討緩和自體顯性多囊腎病程的可行性-第二期多年期研究計畫』,2015/08/01 ~ 2018/7/31 (共同主持人,MOST 104-2314-B-006 -056 -MY3).
  4. 科技部研究計畫『建構即時高靈敏度之牙周病致病菌診斷套件』,2015/08/01 ~ 2016/7/31 (共同主持人,MOST 104-2314-B-006-008-).
  5. 勞動部研究計畫『奈米物質SDS危害測試技術發展與影響因素探討』,2016/02/29 ~ 2016/12/15 (共同主持人).
  6. 勞動部研究計畫『奈米物質風險等級評估與分級管理技術評估』,2015/05/01 ~ 2015/12/31 (共同主持人).
  7. 科技部研究計畫『以高特異性組織標靶奈米粒子包覆抗小分子核糖核苷酸為治療策略以探討緩和自體顯性多囊腎病程的可行性』,2014/08/01 ~ 2015/7/31 (共同主持人,MOST 103-2314-B-006-019-).
  8. 科技部研究計畫『結合奈米金與奈米技術開發新式樣泛用型高靈敏度快速檢測平』,2014/08/01 ~ 2015/7/31 (主持人,MOST 103-2113-M-006-005-).
  9. 科技部萌芽個案計畫『新型奈米生醫材料應用於頭頸部癌治療與診斷研究計畫』,2013/11/01 ~ 2014/12/31 (共同主持人,MOST 102-3011-P-006-006-).
  10. 科技部多年期研究計畫『發展應用於癌細胞治療和藥物輸送的多功能奈米複合材料及其做為非侵入式腦部疾病的治療平台』,2012/12/01 ~ 2014/7/31 (主持人,MOST 101-2113-M-006-006-MY2).
  11. 科技部萌芽個案計畫『新型奈米生醫材料於醫療診治的創新應用研發(I)』,2012/11/01 ~ 2013/12/31 (共同主持人,MOST 101-3011-P-006-005-).
  12. 科技部研究計畫『發展三合一癌症治療平台:結合siRNA與裝載抗癌藥物之中孔洞二氧化矽/金奈米棒之開發』,2011/08/01 ~ 2012/7/31 (主持人,NSC 100-2113-M-006-012).
  13. 勞動部研究計畫『微粒造成細胞株危害指標與影響因素探討(II)』,2013/05/01 ~ 2013/12/31 (共同主持人).
  14. 勞動部研究計畫『微粒造成細胞株危害指標與影響因素探討(I)』,2012/06/01 ~ 2012/12/31 (共同主持人).
  15. 醫療器材跨領域萌芽創新計畫『子計畫五-高靈敏度側流式試劑條檢測系統之開發』,2012/01/01 ~ 2012/12/31 (子計畫主持人,NSC 101-2321-B-006-011).