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08_Yu-Heng Lai

    名   賴昱衡 助理教授
聯絡電話(辦公室)   (02)-28610511#25318
教    研   室   大義館3F    327-1
學    歷  美國喬治亞州 Emory 大學遺傳生化博士
研究領域與專長   分析化學 生物化學 發育生物學
Email   lyh21@ulive.pccu.edu.tw
 

學術著作

SCI papers:

1.Yen-Chang Lin; Cheng Huang; Hsiu-Chen Huang; Ming-Ting Liao; Yu-Heng Lai (2019, Apr). Metabolomics profiling of haloperidol and validation of haloperidol-affected thromboxane activity in the early development of zebrafish. Biochemical and Biophysical Research Communications. (Accepted). 本人為通訊作者.

2.   Cheng Huang, Yu-Ling Huang, Chia-Chi Wang, Yi-Ling Pan, Yu-Heng Lai, and Hsiu-Chen Huang (2019, Feb). Ampelopsin A and ampelopsin C induce apoptosis and metastasis through down-regulating AxL, TYRO3, and FYN expressions in MDA-MB-231 breast cancer cells. Journal of Agricultural and Food Chemistry, 2019, 67 (10), pp 2818–2830.

3.   Erwei Hao, Guofeng Pang, Zhengcai Du, Yu-Heng Lai, Jung-Ren Chen, Jinling Xie, Kai Zhou, Xiaotao Hou, Chung-Der Hsiao and Jiagang Deng (2019, Jan). Peach Kernel Oil Downregulates Expression of Tissue Factor and Reduces Atherosclerosis in ApoE knockout Mice. International Journal of Molecular Science, 2019 Jan; 20(2): 405..

4.   Gilbert Audira, Sreeja Sarasamma, Jung-Ren Chen, Stevhen Juniardi, Bonifasius Putera Sampurna, Sung-Tzu Liang, Yu-Heng Lai, Geng-Ming Lin, Ming-Chia Hsieh and Chung-Der Hsiao (2018, Dec). Zebrafish Mutants Carrying Leptin a (lepa) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color Preference Dysregulation. International Journal of Molecular Science, 2018, 19(12), 4038.

5.   Sreeja Sarasamma, Gilbert Audira, Stevhen Juniardi, Bonifasius Putera Sampurna, Yu-Heng Lai, Erwei Hao, Jung-Ren Chen and Chung-Der Hsiao (2018, Dec). Evaluation of the effects of Carbon 60 nanoparticle exposure in adult zebrafish: A behavioral and biochemical approach to elucidate the mechanism of toxicity. International Journal of Molecular Science, 2018, 19(12), 3853.

6.   Sreeja Sarasamma, Yu-Heng Lai, Sung-Tzu Liang, Kechun Liu *, Chung-Der Hsiao * (2018, Dec). The power of fish models to elucidate skin cancer pathogenesis and impact on the discovery of new therapeutic opportunities. International Journal of Molecular Science, 2018, 19(12), 3929.

7.   Gilbert Audira, Bonifasius Putera Sampurna, Stevhen Juniardi, Sung-Tzu Liang, Yu-Heng Lai and Chung-Der Hsiao (2018, Nov). A Versatile Setup for Measuring Multiple Behavior Endpoints in Zebrafish. Inventions, 2018, 3(4), 75. 本人為通訊作者.

8.   Yu-Heng Lai, Hao-Yun Liu, Chun-Yao Huang, Yat-Pang Chau and Semon Wu (2018, Nov). Mitochondrial DNA-associated TLR9 signaling is a potential serological biomarker for non-small cell lung cancer. Oncology Reports , 2019 Feb;41(2):999-1006. 本人為第一作者.

9.   Hsu-Feng Lu, Yu-Heng Lai, Hsiu-Chen Huang, I-Jung Lee, Lie-Chwen Lin, Hui- Kang Liu, Hsiao-Hsuan Tien, Cheng Huang (2018, Oct). Ginseng-plus-Bai-Hu- Tang ameliorates diet-induced obesity, hepatic steatosis and insulin resistance in mice. Journal of Ginseng Research, in press.

10.   Sreeja Sarasamma, Gilbert Audira, Stevhen Juniardi, Bonifasius Putera Sampurna, Sung-Tzu Liang, Erwei Hao, Yu-Heng Lai and Chung-Der Hsiao (2018, Oct). Zinc chloride exposure inhibits brain acetylcholine level and produces neurotoxic signatures and diminish memory and motor activities in adult zebrafish. International Journal of Molecular Science, 2018, 19(10), 3195.本人為通訊作者.

11.  Xiao-yun Xiong, Yi Liu, Le-tian Shan, Yi-qiao Xu, Jun Liang, Yu-Heng Lai and Chung-Der Hsiao (2018, Oct). Evaluation of collagen mixture on promoting skin wound healing in zebrafish caused by acetic acid administration. Biochemical and Biophysical Research CommunicationsVolume 505, Issue 2, 28 October 2018, Pages 516-522. 本人為通訊作者.

12.  Yu-Heng Lai, Cheng-Pu Sun, Hsiu-Chen Huang, Jui-Chieh Chen, Hui-Kang Liu and Cheng Huang (2018, Sep). Epigallocatechin gallate inhibits hepatitis B virus infection in human liver chimeric mice. BMC Complementary and Alternative Medicine18:248. 本人為第一作者.

13.  Bonifasius Putera Sampurna, Gilbert Audira, Stevhen Juniardi, Yu-Heng Lai,* and Chung-Der Hsiao* (2018, Apr). A Simple ImageJ-Based Method to Measure Cardiac Rhythm in Zebrafish Embryos. Inventions2018, 3(2), 21. 本人為通訊作者.

14.  Szu-Yuan Wu, Nam-Nhut Phan, Shih-Hsin Ho, Yu-Heng Lai, Chih-Hung Tsai, Chung-Han Yang, Han-Gang Yu, Jung-Chieh Wang, Pung-Ling Huang, Yen- Chang Lin (2018, Mar). Metabolomic assessment of arsenite toxicity and novel biomarker discovery in early development of zebrafish embryos. Toxicology LettersVolume 290, 15 June 2018, Pages 116-122.

15.  Gilbert Audira, Bonifasius Putera Sampurna, Stevhen Juniardi, Sung-Tzu Liang, Yu-Heng Lai,* and Chung-Der Hsiao* (2018, Feb). A Simple Setup to Perform

3D Locomotion Tracking in Zebrafish by Using Single Camera. Inventions, 2018, 3(1), 11. 本人為通訊作者.

16.  Hsiu-Chen Huang,Hsu-Feng Lu, Yu-Heng Lai, Chung-Pei Lee, Hui-Kang Liu and Cheng Huang (2018, Feb). Tat-enhanced delivery of the C terminus of HDAg-L inhibits assembly and secretion of hepatitis D virus. Antiviral Research.

17.  Geng-Ming Lin, Yu-Heng Lai, Gilbert Audira and Chung-Der Hsiao (2017, Nov). A Simple Method to Decode the Complete 18-5.8-28S rRNA Repeated Units of Green Algae by Genome Skimming. International Journal of Molecular Science, 2017, 18(11), 2341. MOST 105-2313-B-033-001-MY3.

18.  Jung-Ren Chen, Yu-Heng Lai, Jhih-Jie Tsai and Chung-Der Hsiao (2017, Nov). Live Fluorescent Staining Platform for Drug-Screening and Mechanism-Analysis in Zebrafish for Bone Mineralization. Molecules, 22, 2068.

19.  Yen Chu, Yu-Heng Lai, Ming-Cheng Lee, Yu-Jung Yeh, Yao-Kuang Wu, Wayne Tsao, Chun-Yao Huang and Semon Wu (2017, Nov). Calsyntenin-1, clusterin and neutrophil gelatinase-associated lipocalin are candidate serological biomarkers for lung adenocarcinoma. OncotargetVol. 8, (No. 64), pp: 107964-107976.

20.  Yu-Heng Lai, Yu-Ju Ding, David Moses, Yau-Hung Chen (2017, Aug). Teratogenic Effects of Topiramate in a Zebrafish ModelInternational Journal of Molecular Science, 2017, 18(8), 1721. 本人為第一作者.

21.  Hsiu-Chen Huang, Chung-Pei Lee, Hui-Kang Liu, Ming-Fu Chang, Yu-Heng Lai, Yu-Ching Lee and Cheng Huang (2016, Nov). Cellular Nuclear Export Factors TAP and Aly Are Required for HDAg-L-mediated Assembly of Hepatitis Delta Virus. Journal of Biological Chemistry, 291, p26226-262231.

22.  You-Kang Chang*, Yu-Heng Lai*, Yen Chu, Ming-Cheng Lee, Chun-Yao Huang, Semon Wu (2016, Aug). Haptoglobin is a serological biomarker for adenocarcinoma lung cancer by using the ProteomeLab PF2D combined with mass spectrometry. American Journal of Cancer Research, 6(8):1828-1836. 本人為第一作者.

23. H-C Huang, C-P Lee, H-K Liu, M-F Chang, Y-H Lai, Y-C Lee, and C Huang*, Cellular Nuclear Export Factors TAP and Aly Are Required for HDAg-L-mediated Assembly of Hepatitis Delta Virus, The Journal of Biological Chemistry, 2016, 291, 26226-26238.

24. Y-K Chang#, Y-H Lai#, Y Chu, M-C Lee, C-Y Huang, Semon Wu*, Haptoglobin is a serological biomarker for adenocarcinoma lung cancer by using the ProteomeLab PF2D combined with mass spectrometry, Am J Cancer Res, 2016; 6(8):1828-1836.

25. CJ Phillip, CK Giardina, Y-H Lai, O Kucuk and CS Moreno*, Genistein Cooperates with the Histone Deacetylase Inhibitor Vorinostat to Induce Cell Death in Prostate Cancer Cells, BMC cancer, 2012, 12: 145.

26. Y-H Lai, J Cheng, ME. Feasel, KD. Beste, J Peng, A Nusrat and CS. Moreno*, SOX4 Interacts with Plakoglobin in a Wnt3a-dependent Manner in Prostate Cancer Cells, BMC Cell Biology, 2011, 12:50.

27. Q Long, BA Johnson, AO Osunkoya, Y-H Lai, W Zhou, M Abramovitz, M Xia, M Bouzyk, R Nam, L Sugar, A Stanimirovic, BR Leyland-Jones, AK Seth, JA Petros, CS Moreno*, Protein-coding and MicroRNA Biomarkers of Recurrence of Prostate Cancer Following Radical Prostatectomy, American Journal of Pathology, 2011, Vol. 179, No. 1.

 


Conference papers:

1.盧建銘、賴玲鳳、許桂樹、李銘孝、江育文、林雨聖、楊綺雯、賴昱衡、楊春陵、歐耿良,鋁奈米粉末應用在雷射粉體融化成型積層製造的研究,中華民國力學學會第四十屆全國力學會議,2016,p159.

2.江育文, 盧建銘, 朱力民, 李銘孝, 林雨聖, 賴昱衡, 楊春陵, 歐耿良,金屬奈米粉末應用於雷射粉體熔化成型積層製造之物理特性研究,中華民國力學學會第四十屆全國力學會議,2016, p297.

3. J-M Lu, M-H Lee, Y-W Chiang, L-M Chu, Y-S Lin, Y-H Lai, T-Li Yang and K-L Ou, 3D Printing of Selective Laser Sintering/Melting of Tantalum Nanoparticles, Fifth International Multi-Conference on Engineering and Technology Innovation, 2016.

Posters:

1. M-W Huang, T-W Tang, Y-H Lai, Effects of Graphene Oxide on Embryonic Development in Zebrafish, 中國化學年會, 2016.

2. Z-H Huang, Y-H Lai, Identify the biochemical effects of herbal medicine hm38 on zebrafish embryonic development, 中國化學年會, 2015.

3. Y-H Lai, J Cheng, ME. Feasel, KD. Beste, J Peng, A Nusrat and CS. Moreno, SOX4 Interacts with Plakoglobin in a Wnt3a-dependent Manner in Prostate Cancer Cells, Gordon Research Conference, Davidson, NC, July 24-29, 2011.

4. Y-H Lai, J Peng, J Cheng, and CS Moreno, Comprehensive Characterization of SOX4 Protein Complexes in Prostate Cancer Cells [Abstract], AACR 101st Annual Meeting, Washington, DC, April 17-21, 2010.

5. Lai YH, Seth A, Osunkoya AO, Zhou W, Petros JA, Johnson BA, Nam RK, Barwick BG, Abramovitz M, Bouzyk M, Leyland-Jones B, and Moreno CS, Annual Meeting of the American Urological Association, Chicago, IL, April 25-30, 2009.

6. Moreno CS, Lai YH, Seth A, Osunkoya AO, Zhou W, Petros JA, Johnson BA, Nam RK, Barwick BG, Abramovitz M, and Bouzyk M, Leyland-Jones B. Protein-coding and MicroRNA Biomarker Gene Panels Predictive of Clinical Recurrence in Prostate Cancer. [Oral Presentation] ASIP 2009 Annual Meeting, New Orleans, LA, April 18-22, 2009. Protein-coding and MicroRNA Biomarker Gene Panels Predictive of Clinical Recurrence in Prostate Cancer. FASEB J. 2009; 23 (Meeting Abstracts): p. 361.2

7. Lai YH, Seth A, Osunkoya AO, Zhou W, Petros JA, Johnson BA, Nam RK, Barwick BG, Abramovitz M, Bouzyk M, Leyland-Jones B, and Moreno CS. Protein-coding and MicroRNA Biomarker Gene Panels Predictive of Clinical Recurrence in Prostate Cancer. [Oral Presentation] AACR 2009 Special Conference, Translation of the Cancer Genome, Boston, MA, February 7-9, 2009.

8. Lai YH, Seth A, Osunkoya AO, Zhou W, Petros JA, Johnson BA, Nam RK, Barwick BG, Abramovitz M, Bouzyk M, Leyland-Jones B, and Moreno CS. Protein-coding and MicroRNA Biomarker Gene Panels Predictive of Clinical Recurrence in Prostate Cancer, AACR Special Conference, Advances in Prostate Cancer Research, San Diego, CA, January 21-24, 2009.


   

 

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