化學系暨化學系應用化學碩士班 College of Sciences Department of Chemistry and College of Sciences Master Program, Department of Applied Chemistry

1. Kao, Y. R., Shih, J. Y., Wen, W. C., Ko, Y. P., Chen, B. M., Chan, Y. L., Chu, Y. W., Yang, P. C., Wu, C. W., and Roffler, S. R. Tumor-associated antigen L6 and the invasion of human lung cancer cells. Clinical Cancer Res, 9: 2807-2816, 2003. (SCI: 8.193, 13/202)

2. Wu, C. J., Huang, H. W., Liu, C. Y., Hong, C. F., and Chan, Y. L. Inhibition of SARS-CoV replication by siRNA. Antiviral Res, 65: 45-48, 2005. (SCI: 3.434, 58/254)

3. Wu, C. J. and Chan. Y. L. Coronaviruses and severe acute respiratory syndrome associated coronavirus (SARS-CoV). In: Hefferon, K.L. (Eds.), Recent advances in RNA virus replication, first ed. Transworld research network, Kerala, India, pp. 29-44, 2006.

4. Wu, C. J. and Chan, Y. L. Antiviral applications of RNAi for coronavirus. Expert Opin Investig Drugs, 15: 89-97, 2006. (SCI: 5.432, 18/254)

5. Wu, C. J., Li, T. L., Huang, H. W., Tao, M. H., and Chan, Y. L. Development of an effective Japanese encephalitis virus-specific DNA vaccine. Microbes Infect, 8: 2578-2586, 2006. (SCI: 2.731, 49/119)

6. Chan, Y. L., Chang, T. H., Liao, C. L., and Lin, Y. L. The cellular antiviral protein viperin is attenuated by proteasome-mediated protein degradation in Japanese encephalitis virus-infected cells. Journal of Virolology, 82: 10455-10464, 2008. (SCI: 4.648, 7/32)

7. Cheng, J. Y., Huang, H. N., Tseng, W. C., Li, T. L., Chan, Y. L., Cheng, K. C., and Wu, C. J. Transcutaneous immunization by lipoplex-patch based DNA vaccines is effective vaccination against Japanese encephalitis virus infection. Journal of Controlled Release, 135: 242-249, 2009. (SCI: 7.261, 11/254)

8. Huang, H. N., Li, T. L., Chan, Y. L., Chen, C. L., and Wu, C. J. Transdermal immunization with low-pressure-gene-gun mediated chitosan-based DNA vaccines against Japanese encephalitis virus. Biomaterials, 30: 6017-6025, 2009. (SCI: 8.312, 1/32)

9. Chai, H. J., Li, J. H., Huang, H. N., Li, T. L., Chan, Y. L., Shiau, C. Y., and Wu, C. J. Effects of sizes and conformations of fish scale collagen peptides (FSCPs) on facial skin qualities and transdermal penetration efficiency. Journal of Biomedicine and Biotechnology. Article ID 757301, 9 pages, 2010. (SCI: 2.706, 53/165)

10. Hwang, P. A., Chien, S. Y., Chan, Y. L., Lu, M. K., Kong, Z. L., Wu, C. H., and Wu, C. J. Inhibition of LPS-induced Inflammatory Responses by Sargassum hemiphyllum sulfated polysaccharide extract in RAW 264.7 Macrophage Cells. Journal of Agricultural and Food Chemistry, 59: 2062-2068, 2011. (SCI: 3.107, 2/56)

11. Huang, H. N., Pan, C. Y., Rajanbabu, V., Chan, Y. L., Wu, C. J., and Chen, J. Y. Modulation of immune responses by the antimicrobial peptide, epinecidin (Epi)-1, and establishment of an Epi-1-based inactivated vaccine. Biomaterials, 32: 3627-3636, 2011. (SCI: 8.312, 1/32)

12. Wu, C. J., Wang, H., Chan, Y. L., and Li, T. L. Passive immune-protection of small abalone against Vibrio alginolyticus infection by anti-Vibrio IgY-encapsulated feed. Fish & Shellfish Immunology, 30: 1042-1048, 2011. (SCI: 3.034, 3/129)

13. Wang, H., Lai, Y.J., Chan, Y.L., Li, T.L., and Wu, C. J. Epigallocatechin -3- gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia. Cancer Letters, 305: 40-49, 2011. (SCI: 5.016, 33/202)

14. Huang, H. N., Rajanbabu, V., Pan, C. Y., Chan, Y. L., Chen, J. Y., and Wu, C. J. Modulation of the immune-related gene responses to protect mice against Japanese encephalitis virus using the antimicrobial peptide, tilapia hepcidin 1-5. Biomaterials, 32: 6804-6814, 2011. (SCI: 8.312, 1/32)

15. Chai, H. J., Chan, Y. L., Li, T. L., Chen, Y. C., Wu, C. H., Shiau, C. Y., and Wu, C. J. Composition characterization of Myctophids (Benthosema pterotum): antioxidation and safety evaluations for Myctophids protein hydrolysates. Food Research International, 46:118-126, 2012. (SCI: 3.050, 14/123)

16. Wang, H.*, Chan, Y. L.*, Li, T. L., and Wu, C. J. Improving cachectic symptoms and immune strength of tumor-bearing mice in chemotherapy by a combination of Scutellaria baicalensis and Qing-Shu-Yi-Qi-Tang. European Journal of Cancer, 48:1074-1084, 2012. (*equal contribution, SCI: 4.819, 41/202)

17. Chiu, Y. H.*, Chan, Y. L.*, Li, T. L., and Wu, C. J. Inhibition of Japanese encephalitis virus infection by the sulfated polysaccharide extracts from Ulva lactuca. Marine Biotechnology. 14:468-478, 2012. (SCI: 3.152, 8/102)

18. Chiu, Y. H.*, Chan, Y. L.*, Tsai, L. W., Li, T. L., and Wu, C. J. Prevention of human enterovirus 71 infection by kappa carrageenan. Antiviral Research, 95: 128-134, 2012. (* equal contribution, SCI: 3.434, 58/254)

19. Wang, H.*, Chan, Y. L.*, Li, T. L., Bauer, B. A., Hsia, S., Wang, C. H., Huang, J. S., Wang, H. M., Yeh, K. Y., Huang, T. H, Wu, G. J., and Wu, C. J. Reduction of splenic immunosuppressive cells and enhancement of anti-tumor immunity by synergy of fish oil and selenium yeast. PLoS One, 8:e52912, 2013. doi:10.1371/journal.pone.0052912. (*equal contribution, SCI: 3.534, 8/55)

20. Huang, H. N., Rajanbabu, V., Pan, C. Y., Chan, Y. L., Wu, C. J., and Chen, J. Y. A cancer vaccine based on the marine antimicrobial peptide pardaxin (GE33) for control of bladder-associated tumors. Biomaterials, 34: 10151-10159, 2013. (SCI: 8.312, 1/32)

21. Huang, H. N., Rajanbabu, V., Pan, C. Y., Chan, Y. L., Wu, C. J., and Chen, J. Y. Use of the antimicrobial peptide Epinecidin-1 to protect against MRSA infection in mice with skin injuries. Biomaterials, 34: 10319-10327, 2013. (SCI: 8.312, 1/32)

22. Chai, H. J., Chan, Y. L., Li, T. L., Shiau, C. Y., and Wu, C. J. Evaluation of lanternfish (Benthosema pterotum) hydrolysates as antioxidants against hydrogen peroxide induced oxidative injury. Food Research International, 54: 1409-1418, 2013. (SCI: 3.050, 14/123)

23. Huang, H. N., Pan, C. Y., Chan, Y. L., Chen, J. Y., and Wu, C. J. Use of the antimicrobial peptide pardaxin (GE33) to protect against MRSA infection in mice with skin injuries. Antimicrobial Agents and Chemotherapy, 58: 1538-1545, 2014. (SCI: 4.451, 27/254)

24. Chen, C. C., Hsieh, D. S., Huang, K. J., Chan, Y. L., Hong, P. D., Yeh, M. K., and Wu, C. J. Improving anticancer efficacy of (-)-epigallocatechin-3-gallate gold nanoparticles in murine B16F10 melanoma cells. Drug Design, Development and Therapy, 8: 459-474, 2014. (SCI: 3.026, 75/254)

25. Yang, S.M., Chan, Y.L., Hua, K.F., Chang, J.M., Chen, H.L., Tsai, Y.J., Hsu, Y.J., Chao, L.K., Feng-Ling, Y., Tsai, Y.L., Wu, S.H., Wang, Y.F., Tsai, C.L., Chen, A., Ka, S.M.. Osthole improves an accelerated focal segmental glomerulosclerosis model in the early stage by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF-κB-mediated COX-2 expression and apoptosis. Free Radical Biology and Medicine, 73: 260-269, 2014. (SCI: 5.271, 17/122)

學位論文

博士論文：抗病毒蛋白Viperin基因表現調節及其抗病毒作用之研究（Study of the gene expression regulation and anti-viral function of Viperin）

碩士論文：Characterization of the intracellular interactions of the 5T4 oncofotal antigen

研討會發表(Conference presentation)

專書、委託報告與研討會全文(Book sections, technical reports & conference articles)